Port 465 was originally registered for SMTPS (SMTP over SSL). After a brief stint in that function, port 465 was reassigned for a different use and deprecated. Despite that fact, many ISPs and cloud hosting providers still support port 465 for SMTP submission.
Instead, the Internet Assigned Numbers Authority (IANA), who maintains much of the core internet infrastructure, registered port 465 for SMTPS. The purpose was to establish a port for SMTP to operate using Secure Sockets Layer (SSL). SSL is commonly used for encrypting communications over the internet.
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So a good solution is to simply change the port to 587 or 2525 (if you’re using an unencrypted connection) and 465 or 25025 for a SSL connection. Remember anyway that only a professional SMTP service can guarantee the highest delivery rate, avoiding completely all these sending problems.
If you want to connect SMTP service to send an email, you need to provide an SMTP IP address, Port number and login credentials. SMTP Port Numbers > The default SMTP port number is : 25
Enter your full email address as the username and your password. Click the Advanced tab and change the Outgoing server (SMTP) port. If you want to use SSL, then change the port to 465 and select SSL from the encryption drop-down menu. If you don’t want to use SSL, then change the port to 587.
It’s very simple: you just need to open your mail client’s configuration panel and flag “Use SSL/TLS” in the “Connection security” field. Remember also to set the right SMTP SSL port for the email transmission – normally, port 465.